报告人简介

王亮，中国科学院心理研究所研究员，博士生导师，中国科学院心理健康重点实验室主任，中国科学院大学心理学系岗位教授。担任中国心理学会副秘书长、中国心理学会生理心理学专委会副主委、中国神经科学学会认知生物学分会副主委等。研究成果以通讯作者发表在Neuron,Science Advances（2篇）,Current Biology（2篇）,Annals of Neurology等权威期刊。

内容简介

A growing body of studies have revealed many spatial cells in hippocampal formation, and similar brain activity patterns at the macroscopic level. With human intracranial EEG recordings, we found that theta power was hexadirectionally modulated by movement direction in the entorhinal cortex and medial prefrontal cortex. Inter-regional theta oscillations formed a synchronized hippocampo-cortical network, speeding up information transfer and facilitating memory-guided spatial navigation. Theta-based goal distance modulation and neural timescales gradually change along the hippocampal longitudinal axis, indicating a coarse-to-fine goal distance representation in the human hippocampus. Memory reactivation following learning of object-location associations increased hippocampal ripples and cortical spindles.